[2.2]Paracyclophane derivatives containing tetrathiafulvalene moieties

• Laura G. Sarbu,
• Lucian G. Bahrin,
• Peter G. Jones,
• Lucian M. Birsa and
• Henning Hopf

Beilstein J. Org. Chem. 2015, 11, 1917–1921, doi:10.3762/bjoc.11.207

• the rigid framework and the short distance between the two aromatic rings within the [2.2]paracyclophane unit. Besides investigations of the geometry and of transannular interactions, special attention has been paid to the ability of these compounds to form charge-transfer complexes [6][7][8][9]. A

Selected synthetic strategies to cyclophanes

• Sambasivarao Kotha,
• Mukesh E. Shirbhate and
• Gopalkrushna T. Waghule

Beilstein J. Org. Chem. 2015, 11, 1274–1331, doi:10.3762/bjoc.11.142

• electronic effect through transannular interactions. Rajakumar and Selvam [108] also synthesized chiral stilbenophane 89 with small to large cavity sizes. These chiral stilbenophanes forms a complex with tetracyanoethylene (TCNE) and tetracyanoquinodimethane (TCNQ). The same group also reported on the

Selenium halide-induced bridge formation in [2.2]paracyclophanes

• Laura G. Sarbu,
• Henning Hopf,
• Peter G. Jones and
• Lucian M. Birsa

Beilstein J. Org. Chem. 2014, 10, 2550–2555, doi:10.3762/bjoc.10.266

• ; Introduction Starting with their discovery in 1949, the [2.2]paracyclophane molecule and its derivatives have been intensely studied [1][2][3]. Of particular interest are the geometry and transannular interactions of these molecules, the study of electrophilic aromatic substitution reactions involving these

Total synthesis of the proposed structure of astakolactin

• Takayuki Tonoi,
• Keisuke Mameda,
• Moe Fujishiro,
• Yutaka Yoshinaga and
• Isamu Shiina

Beilstein J. Org. Chem. 2014, 10, 2421–2427, doi:10.3762/bjoc.10.252

• saturated medium-sized lactones, which are generally difficult to construct because of the ring strain and transannular interactions [27][28], can be effectively prepared [29][30]. Therefore, in order to determine the chemical structure and the expected biological activity of compound 1, we executed the

The preferred conformation of erythro- and threo-1,2-difluorocyclododecanes

• Yi Wang,
• Peer Kirsch,
• Tomas Lebl,
• Alexandra M. Z. Slawin and
• David O'Hagan

Beilstein J. Org. Chem. 2012, 8, 1271–1278, doi:10.3762/bjoc.8.143

• –F bond endo into the ring, and appear to benefit from C–CHF–C angle widening, which relaxes 1,4-H,H transannular interactions. Keywords: alicyclic chemistry; conformational analysis; cyclododecane; 19F NMR; organo-fluorine chemistry; transannular interactions; Introduction The conformation of

• to a high level of disorder, but the diffraction data was used as the basis of a further computational analysis, and the structure in Figure 1 emerged as their consensus structure [5][6]. The structure is tensioned by transannular interactions in which there are four endo hydrogens, one on each edge